AKIP1

Across TCGA cell cohorts, AKIP1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AKIP1-associated genes across cancer lineages are PPP1R2C, CST8, and PRAMEF7. Each is linked with AKIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AKIP1-to-partner and partner-to-AKIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPP1R2C grouped by AKIP1-low versus AKIP1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKIP1→partner) and Y-score (partner→AKIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PPP1R2C →	+0.307	+5.539	<.001	.003	3	1
BLOOD_Leukemia	CST8 →	+0.062	+5.969	<.001	.001	3	1
BLOOD_Leukemia	PRAMEF7 →	+0.012	+5.539	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

PPP1R2C by AKIP1 expression — BLOOD_Leukemia

Explore this box plot interactively →