AKIP1

Across TCGA cell cohorts, AKIP1 mutation is significantly associated with the mutation status of many other genes, with 215 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AKIP1-associated genes across cancer lineages are AVPR1A, BPIFA2, and LIPT1. Each is linked with AKIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AKIP1-to-partner and partner-to-AKIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVPR1A grouped by AKIP1-low versus AKIP1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKIP1→partner) and Y-score (partner→AKIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	AVPR1A →	+4.321	+5.285	.005	.005	1	2
BLOOD_Leukemia	BPIFA2 →	+6.321	+6.321	.001	.001	1	2
BLOOD_Leukemia	LIPT1 →	+4.736	+5.560	.003	.003	1	2
BLOOD_Leukemia	SIDT2 →	+4.000	+5.050	.008	.008	1	2
BLOOD_Leukemia	FAM50A →	+4.736	+5.560	.003	.003	1	2
BLOOD_Leukemia	SEMA3A →	+4.000	+5.050	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 215 associations by consensus.

AVPR1A by AKIP1 expression — BLOOD_Leukemia

Explore this box plot interactively →