AKAP9

Across TCGA patient cohorts, AKAP9 protein abundance is significantly associated with the RNA expression of many other genes, with 19,986 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible AKAP9-associated genes across cancer lineages are ZNHIT1, IFT22, and BUD23. Each is linked with AKAP9 in more than 6 cancer types. Because this analysis shows association rather than direction, both AKAP9-to-partner and partner-to-AKAP9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AKAP9 versus ZNHIT1 in UCEC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKAP9→partner) and Y-score (partner→AKAP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNHIT1 →	+0.848	+0.259	<.001	<.001	3	7
UCEC	IFT22 →	+0.974	+0.260	<.001	<.001	3	7
HNSC	BUD23 →	+0.372	+0.195	.008	.003	3	7
HNSC	GTPBP10 →	+0.636	+0.209	<.001	<.001	3	5
HNSC	BET1 →	+0.637	+0.251	<.001	<.001	3	5
HNSC	AGFG2 →	+0.871	+0.288	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,986 associations by consensus.

AKAP9 vs ZNHIT1 — UCEC

Explore this scatter interactively →