AKAP8P1

Across TCGA patient cohorts, AKAP8P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,588 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AKAP8P1-associated GO terms across cancer lineages are DNA replication, Negative regulation of chromosome organization, and Mitotic sister chromatid segregation. Each is linked with AKAP8P1 in more than 18 cancer types. Because this analysis shows association rather than direction, both AKAP8P1-to-partner and partner-to-AKAP8P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication grouped by AKAP8P1-low versus AKAP8P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKAP8P1→partner) and Y-score (partner→AKAP8P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	DNA replication →	+0.057	+0.484	<.001	<.001	3	19
STAD	Negative regulation of chromosome organization →	+0.060	+0.352	<.001	<.001	3	18
STAD	Mitotic sister chromatid segregation →	+0.068	+0.411	<.001	<.001	3	18
STAD	Positive regulation of protein ubiquitination →	+0.048	+0.321	<.001	<.001	3	18
STAD	Mitotic spindle assembly →	+0.061	+0.391	<.001	<.001	3	17
STAD	Negative regulation of double-strand break repair via homologous recombination →	+0.049	+0.268	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,588 associations by consensus.

DNA replication by AKAP8P1 expression — STAD

Explore this box plot interactively →