AKAP6

Across TCGA patient cohorts, AKAP6 protein abundance is significantly associated with the protein abundance of many other proteins, with 7,590 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AKAP6-associated proteins across cancer lineages are SSR3, STXBP5, and TAPT1_S523. Each is linked with AKAP6 in more than 2 cancer types. Because this analysis shows association rather than direction, both AKAP6-to-partner and partner-to-AKAP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AKAP6 versus SSR3 in UCEC, with a Pearson correlation of -0.46.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AKAP6→partner) and Y-score (partner→AKAP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SSR3 →	-0.975	-1.231	.001	.003	2	3
GBM	STXBP5 →	+0.328	+0.236	<.001	.001	3	2
HNSC	TAPT1_S523 →	-0.956	-0.761	<.001	.001	3	2
GBM	WBP2 →	+0.395	+0.378	<.001	<.001	3	2
GBM	DCTN1 →	+0.336	+0.415	<.001	<.001	3	2
HNSC	HMGXB4_S502 →	-0.351	-1.022	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,590 associations by consensus.

AKAP6 vs SSR3 — UCEC

Explore this scatter interactively →