AKAP5

Across TCGA patient cohorts, AKAP5 mutation is significantly associated with the RNA expression of many other genes, with 3,950 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AKAP5-associated genes across cancer lineages are RNU6-362P, RN7SL607P, and LINC02330. Each is linked with AKAP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both AKAP5-to-partner and partner-to-AKAP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-362P grouped by AKAP5-low versus AKAP5-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKAP5→partner) and Y-score (partner→AKAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-362P →	+0.393	+5.263	<.001	.001	3	2
CESC	RN7SL607P →	+0.124	+3.333	.003	.004	3	2
BLCA	LINC02330 →	+0.095	+5.329	.006	.006	3	2
BLCA	LINC01916 →	+0.176	+6.018	<.001	.002	3	2
COAD	LIN28AP2 →	+0.084	+3.836	<.001	.001	3	2
COAD	DYNLT3P2 →	+0.441	+3.920	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,950 associations by consensus.

RNU6-362P by AKAP5 expression — CESC

Explore this box plot interactively →