AKAP4

Across TCGA cell cohorts, AKAP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 659 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AKAP4-associated GO terms across cancer lineages are Myeloid cell development, Neuropeptide signaling pathway, and Response to lead ion. Each is linked with AKAP4 in more than 2 cancer types. Because this analysis shows association rather than direction, both AKAP4-to-partner and partner-to-AKAP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myeloid cell development grouped by AKAP4-low versus AKAP4-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKAP4→partner) and Y-score (partner→AKAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Myeloid cell development →	+0.123	+0.055	<.001	.004	3	3
SKIN	Neuropeptide signaling pathway →	-0.059	-0.002	.007	.007	3	2
BLOOD_Leukemia	Response to lead ion →	+0.142	+0.085	<.001	.003	3	2
BLOOD_Leukemia	Regulation of triglyceride catabolic process →	+0.145	+0.101	<.001	.006	3	2
BLOOD_Leukemia	Oligopeptide import across plasma membrane →	-1.077	-0.055	<.001	.004	3	2
BLOOD_Leukemia	Dipeptide import across plasma membrane →	-1.077	-0.055	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 659 associations by consensus.

Myeloid cell development by AKAP4 expression — BLOOD_Leukemia

Explore this box plot interactively →