Across TCGA cell cohorts, AKAP17A mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AKAP17A-associated genes across cancer lineages are C16orf92, SERPINA12, and KRTAP1-1. Each is linked with AKAP17A in more than 1 cancer types. Because this analysis shows association rather than direction, both AKAP17A-to-partner and partner-to-AKAP17A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKAP17A→partner) and Y-score (partner→AKAP17A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	C16orf92 →	+0.194	+4.037	<.001	.004	3	2
PANCREAS	SERPINA12 →	+0.010	+4.029	<.001	.007	3	1
PANCREAS	KRTAP1-1 →	+0.169	+3.669	<.001	.008	3	1
PANCREAS	IQCF6 →	+0.091	+4.139	<.001	.001	3	1
PANCREAS	OTC →	+1.089	+3.491	.001	.008	3	1
UPPER_AERODIGESTIVE_TRACT	HMX3 →	+0.513	+3.584	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration

AKAP17A survival (RNA) · tumor vs normal (RNA) · all AKAP17A data types