AKAP13

Across TCGA patient cohorts, AKAP13 protein abundance is significantly associated with the RNA expression of many other genes, with 14,048 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AKAP13-associated genes across cancer lineages are PTGER4, RAB27A, and CCR2. Each is linked with AKAP13 in more than 5 cancer types. Because this analysis shows association rather than direction, both AKAP13-to-partner and partner-to-AKAP13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AKAP13 versus PTGER4 in GBM, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKAP13→partner) and Y-score (partner→AKAP13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PTGER4 →	+1.044	+0.287	<.001	.001	3	6
GBM	RAB27A →	+0.641	+0.310	<.001	<.001	3	6
COAD	CCR2 →	+0.997	+0.168	<.001	.003	3	5
GBM	ALOX5 →	+0.735	+0.259	.001	.002	3	5
OV	RAC2 →	+0.839	+0.587	.008	<.001	3	5
GBM	PTPN22 →	+0.724	+0.310	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,048 associations by consensus.

AKAP13 vs PTGER4 — GBM

Explore this scatter interactively →