AKAP13

Across TCGA cell cohorts, AKAP13 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,985 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible AKAP13-associated GO terms across cancer lineages are Negative regulation of autophagy, Regulation of protein-containing complex disassembly, and Negative regulation of myoblast fusion. Each is linked with AKAP13 in more than 16 cancer types. Because this analysis shows association rather than direction, both AKAP13-to-partner and partner-to-AKAP13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of autophagy grouped by AKAP13-low versus AKAP13-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKAP13→partner) and Y-score (partner→AKAP13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of autophagy →	+0.092	+1.101	<.001	.001	3	17
BREAST	Regulation of protein-containing complex disassembly →	+0.052	+0.883	<.001	<.001	3	16
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.137	+0.947	.001	.006	2	16
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.133	+0.923	.001	.006	2	16
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.075	+0.772	<.001	<.001	3	14
OESOPHAGUS	Endosomal transport →	+0.073	+1.366	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,985 associations by consensus.

Negative regulation of autophagy by AKAP13 expression — OESOPHAGUS

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