AKAP12

Across TCGA patient cohorts, AKAP12 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,153 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible AKAP12-associated proteins across cancer lineages are AKAP12_S514, AKAP12_S1331, and AKAP12_S1395. Each is linked with AKAP12 in more than 9 cancer types. Because this analysis shows association rather than direction, both AKAP12-to-partner and partner-to-AKAP12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AKAP12 versus AKAP12_S514 in BRCA, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AKAP12→partner) and Y-score (partner→AKAP12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AKAP12_S514 →	+1.388	+1.295	<.001	<.001	3	10
UCEC	AKAP12_S1331 →	+0.971	+1.573	<.001	<.001	3	9
PDAC	AKAP12_S1395 →	+0.883	+0.673	<.001	<.001	3	9
BRCA	AKAP12_S286 →	+1.397	+1.261	<.001	<.001	3	9
OV	AKAP12_S627 →	+1.334	+1.866	<.001	.001	3	9
BRCA	VCL →	+0.460	+1.098	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,153 associations by consensus.

AKAP12 vs AKAP12_S514 — BRCA

Explore this scatter interactively →