AKAP1

Across TCGA pan-cancer cohorts, AKAP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated AKAP1 data layer compared with 19 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher AKAP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated AKAP1 expression acts as an unfavorable survival marker, although some lineages such as COAD and UCEC show a favorable association.

COAD, UCEC, and HNSC are the cancer types where AKAP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Quartile	All	1.000	0.834	.011	90	view →
UCEC	OS	Median	All	0.986	0.837	.005	40	view →
HNSC	DFS	Median	All	0.681	0.853	.003	34	view →
LUAD	OS	Quartile	All	0.972	0.701	.001	27	view →
LSCC	OS	Quartile	II,III,IV	1.000	0.602	.014	10	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

AKAP1–COAD (DFS)

Open the COAD breakdown →