AKAP1

Across TCGA cell cohorts, AKAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,338 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible AKAP1-associated GO terms across cancer lineages are Meiotic chromosome condensation, Negative regulation of DNA-templated transcription, elongation, and Nucleosome disassembly. Each is linked with AKAP1 in more than 12 cancer types. Because this analysis shows association rather than direction, both AKAP1-to-partner and partner-to-AKAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Meiotic chromosome condensation grouped by AKAP1-low versus AKAP1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKAP1→partner) and Y-score (partner→AKAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Meiotic chromosome condensation →	+0.183	+1.289	<.001	<.001	3	13
BONE	Negative regulation of DNA-templated transcription, elongation →	+0.131	+1.001	<.001	<.001	3	13
BONE	Nucleosome disassembly →	+0.226	+1.355	<.001	<.001	3	13
BONE	Host-mediated activation of viral transcription →	+0.107	+0.956	<.001	<.001	3	13
BONE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.154	+1.144	.003	.003	3	12
BONE	Regulation of peptidase activity →	-0.199	-1.071	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,338 associations by consensus.

Meiotic chromosome condensation by AKAP1 expression — BONE

Explore this box plot interactively →