AK9

Across TCGA cell cohorts, AK9 mutation is significantly associated with the RNA expression of many other genes, with 558 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AK9-associated genes across cancer lineages are OPN1MW, OR52E2, and FXR2. Each is linked with AK9 in more than 1 cancer types. Because this analysis shows association rather than direction, both AK9-to-partner and partner-to-AK9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPN1MW grouped by AK9-low versus AK9-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AK9→partner) and Y-score (partner→AK9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OPN1MW →	+0.004	+4.392	<.001	.004	3	2
LUNG_NSCLC_LUAD	OR52E2 →	+0.200	+3.150	<.001	.006	3	2
LARGE_INTESTINE	FXR2 →	+0.638	+3.364	.001	.002	3	2
LARGE_INTESTINE	GRSF1 →	+0.632	+3.082	<.001	.007	3	2
LARGE_INTESTINE	PEMT →	+0.577	+3.451	.002	.002	3	2
BLOOD_Leukemia	NKX3-1 →	+1.578	+2.489	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 558 associations by consensus.

OPN1MW by AK9 expression — SOFT_TISSUE

Explore this box plot interactively →