AK8

Across TCGA patient cohorts, AK8 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,646 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible AK8-associated proteins across cancer lineages are IFT74, LZTFL1, and TTC21B. Each is linked with AK8 in more than 6 cancer types. Because this analysis shows association rather than direction, both AK8-to-partner and partner-to-AK8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AK8 versus IFT74 in GBM, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AK8→partner) and Y-score (partner→AK8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	IFT74 →	+0.403	+0.874	<.001	<.001	3	6
BRCA	LZTFL1 →	+0.675	+1.011	<.001	<.001	3	6
COAD	TTC21B →	+0.590	+0.450	.007	.005	2	7
UCEC	EFCAB7 →	+0.347	+0.925	<.001	<.001	3	5
GBM	SPA17 →	+0.744	+0.666	<.001	<.001	3	5
BRCA	IFT122 →	+0.403	+0.958	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,646 associations by consensus.

AK8 vs IFT74 — GBM

Explore this scatter interactively →