AK8

Across TCGA patient cohorts, AK8 protein abundance is significantly associated with the RNA expression of many other genes, with 1,411 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AK8-associated genes across cancer lineages are SPEF1, CCDC114, and RSPH4A. Each is linked with AK8 in more than 2 cancer types. Because this analysis shows association rather than direction, both AK8-to-partner and partner-to-AK8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AK8 versus SPEF1 in UCEC, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AK8→partner) and Y-score (partner→AK8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SPEF1 →	+2.642	+0.838	<.001	.005	3	3
UCEC	CCDC114 →	+1.990	+0.991	.001	<.001	3	3
UCEC	RSPH4A →	+2.499	+0.775	<.001	.005	3	3
UCEC	PACRG →	+1.671	+0.959	.004	<.001	3	3
UCEC	C6orf118 →	+2.845	+0.978	<.001	<.001	3	3
UCEC	CFAP94 →	+1.546	+0.817	.004	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,411 associations by consensus.

AK8 vs SPEF1 — UCEC

Explore this scatter interactively →