AK6P2

Across TCGA pan-cancer cohorts, AK6P2 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of AK6P2’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where AK6P2 RNA is repressed in tumor relative to normal tissue. In most cancer types AK6P2 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

THCA, KIRC, and LUSC are the cancer types where AK6P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AK6P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	II,III,IV	−0.036	.023	3	view →
KIRC	Male	II,III,IV	−0.029	.031	1	view →
LUSC	All	All	−0.017	.016	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

AK6P2–THCA

Open the THCA breakdown →