AK6

Across TCGA pan-cancer cohorts, AK6 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated AK6 data layer compared with 21 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher AK6 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated AK6 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

UCEC, CCRCC, and LUAD are the cancer types where AK6 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	All	1.000	0.838	.011	42	view →
CCRCC	DFS	Quartile	III,IV	0.354	0.794	<.001	23	view →
LUAD	OS	Median	All	0.604	0.946	.004	21	view →
LSCC	DFS	Tertile	II,III,IV	1.000	0.813	.021	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

AK6–UCEC (OS)

Open the UCEC breakdown →