AK6

Across TCGA cell cohorts, AK6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,761 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible AK6-associated GO terms across cancer lineages are Dihydrofolate metabolic process, DNA replication, and DNA damage checkpoint signaling. Each is linked with AK6 in more than 11 cancer types. Because this analysis shows association rather than direction, both AK6-to-partner and partner-to-AK6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dihydrofolate metabolic process grouped by AK6-low versus AK6-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AK6→partner) and Y-score (partner→AK6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Dihydrofolate metabolic process →	+0.154	+0.776	<.001	.001	3	12
UPPER_AERODIGESTIVE_TRACT	DNA replication →	+0.088	+0.618	.003	.001	3	11
UPPER_AERODIGESTIVE_TRACT	DNA damage checkpoint signaling →	+0.069	+0.565	.002	.005	3	11
OESOPHAGUS	Positive regulation of rRNA processing →	+0.133	+0.849	.003	<.001	2	12
UPPER_AERODIGESTIVE_TRACT	Signal transduction in response to DNA damage →	+0.049	+0.513	<.001	.004	3	11
URINARY_TRACT	Microtubule polymerization →	+0.095	+0.716	.001	.006	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,761 associations by consensus.

Dihydrofolate metabolic process by AK6 expression — BREAST

Explore this box plot interactively →