AK4

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AK4 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,615 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AK4-associated proteins across cancer lineages are BSG, ABI3, and MDM1_S601. Each is linked with AK4 in more than 4 cancer types. Because this analysis shows association rather than direction, both AK4-to-partner and partner-to-AK4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AK4 versus BSG in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AK4→partner) and Y-score (partner→AK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCBSG →+0.396+1.230<.001<.00135
GBMABI3 →-0.497-0.736<.001<.00135
HNSCMDM1_S601 →-0.434-0.759.003.00135
UCECPRKCQ_T538 →-1.446-0.948.002.00535
LUADPLOD2 →+0.795+1.045<.001<.00135
HNSCSAMHD1 →-0.468-0.679<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,615 associations by consensus.

AK4 vs BSG — LSCC

Per-sample scatter of AK4 vs BSG in LSCC (Pearson r = 0.47).

Explore this scatter interactively →

Exploration