AK4

Across TCGA cell cohorts, AK4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,914 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible AK4-associated GO terms across cancer lineages are GTP metabolic process, Nucleoside diphosphate biosynthetic process, and Hypoxia-inducible factor-1alpha signaling pathway. Each is linked with AK4 in more than 12 cancer types. Because this analysis shows association rather than direction, both AK4-to-partner and partner-to-AK4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GTP metabolic process grouped by AK4-low versus AK4-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AK4→partner) and Y-score (partner→AK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	GTP metabolic process →	+0.142	+2.300	<.001	<.001	3	13
OVARY	Nucleoside diphosphate biosynthetic process →	+0.138	+1.277	<.001	.001	3	11
CNS	Hypoxia-inducible factor-1alpha signaling pathway →	+1.092	+2.218	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	ADP biosynthetic process →	+0.176	+1.397	<.001	<.001	3	11
OVARY	Nucleoside diphosphate metabolic process →	+0.096	+1.134	<.001	<.001	3	11
OVARY	Ribonucleoside diphosphate biosynthetic process →	+0.112	+0.938	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,914 associations by consensus.

GTP metabolic process by AK4 expression — LUNG_SCLC

Explore this box plot interactively →