AK3P2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AK3P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,083 significant associations in total. STAD shows the largest number of these associations.

The most reproducible AK3P2-associated GO terms across cancer lineages are Cellular response to oxidative stress, Regulation of cell projection assembly, and Positive regulation of canonical Wnt signaling pathway. Each is linked with AK3P2 in more than 24 cancer types. Because this analysis shows association rather than direction, both AK3P2-to-partner and partner-to-AK3P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to oxidative stress grouped by AK3P2-low versus AK3P2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AK3P2→partner) and Y-score (partner→AK3P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCACellular response to oxidative stress →+0.052+0.261<.001<.001325
DLBCRegulation of cell projection assembly →+0.045+0.249.004<.001324
STADPositive regulation of canonical Wnt signaling pathway →+0.046+0.178<.001<.001323
ESCAHematopoietic progenitor cell differentiation →+0.043+0.221.003<.001323
STADEstablishment of cell polarity →+0.046+0.186<.001<.001323
ESCARegulation of intracellular protein transport →+0.050+0.204.002<.001323
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,083 associations by consensus.

Cellular response to oxidative stress by AK3P2 expression — ESCA

Box plot of Cellular response to oxidative stress in AK3P2-low vs AK3P2-high samples in ESCA.

Explore this box plot interactively →

Exploration