AK3

Across TCGA patient cohorts, AK3 protein abundance is significantly associated with the RNA expression of many other genes, with 9,651 significant associations in total. COAD shows the largest number of these associations.

The most reproducible AK3-associated genes across cancer lineages are STIL, KIF18A, and CCNB2. Each is linked with AK3 in more than 7 cancer types. Because this analysis shows association rather than direction, both AK3-to-partner and partner-to-AK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AK3 versus STIL in UCEC, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AK3→partner) and Y-score (partner→AK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STIL →	-0.724	-0.344	.001	.001	3	8
LSCC	KIF18A →	-0.821	-0.351	<.001	.001	3	7
GBM	CCNB2 →	-0.747	-0.358	<.001	<.001	3	7
UCEC	CDC20 →	-1.219	-0.278	<.001	.006	3	7
GBM	KIF14 →	-0.828	-0.371	<.001	<.001	3	7
UCEC	KIF23 →	-0.742	-0.335	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,651 associations by consensus.

AK3 vs STIL — UCEC

Explore this scatter interactively →