AK2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AK2 protein abundance is significantly associated with the protein abundance of many other proteins, with 20,013 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AK2-associated proteins across cancer lineages are AIFM1, SUCLG1, and SUCLG2. Each is linked with AK2 in more than 9 cancer types. Because this analysis shows association rather than direction, both AK2-to-partner and partner-to-AK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AK2 versus AIFM1 in OV, with a Pearson correlation of 0.62.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AK2→partner) and Y-score (partner→AK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVAIFM1 →+0.691+0.506<.001<.001310
COADSUCLG1 →+0.455+0.318<.001<.00139
UCECSUCLG2 →+0.486+0.453<.001<.00139
CCRCCTIMM9 →+0.500+0.392<.001<.00139
GBMHMGCL →+0.436+0.303<.001<.00139
OVTIMM13 →+0.600+0.553<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,013 associations by consensus.

AK2 vs AIFM1 — OV

Per-sample scatter of AK2 vs AIFM1 in OV (Pearson r = 0.62).

Explore this scatter interactively →

Exploration