Across TCGA cell cohorts, AJAP1 mutation is significantly associated with the drug of many other genes, with 18 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AJAP1-associated genes across cancer lineages are Nutlin-3a (-), Niraparib, and PAK_5339. Each is linked with AJAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AJAP1-to-partner and partner-to-AJAP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AJAP1→partner) and Y-score (partner→AJAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Nutlin-3a (-) →	+0.988	+2.868	.003	.022	3	1
LARGE_INTESTINE	Niraparib →	+0.382	+2.868	.023	.022	3	1
LARGE_INTESTINE	PAK_5339 →	+0.297	+2.678	.036	.037	3	1
LARGE_INTESTINE	150412 →	+0.391	+3.000	.013	.017	3	1
LARGE_INTESTINE	Ispinesib Mesylate →	+0.682	+2.874	.027	.021	3	1
LARGE_INTESTINE	CD532 →	+0.476	+2.874	.011	.021	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

AJAP1 survival (RNA) · tumor vs normal (RNA) · all AJAP1 data types