AIPL1

Across TCGA patient cohorts, AIPL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,907 significant associations in total. STAD shows the largest number of these associations.

The most reproducible AIPL1-associated GO terms across cancer lineages are Positive regulation of canonical NF-kappaB signal transduction, Negative regulation of response to biotic stimulus, and Negative regulation of viral genome replication. Each is linked with AIPL1 in more than 17 cancer types. Because this analysis shows association rather than direction, both AIPL1-to-partner and partner-to-AIPL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of canonical NF-kappaB signal transduction grouped by AIPL1-low versus AIPL1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AIPL1→partner) and Y-score (partner→AIPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of canonical NF-kappaB signal transduction →	+0.064	+0.096	<.001	<.001	3	18
STAD	Negative regulation of response to biotic stimulus →	+0.063	+0.122	<.001	<.001	3	18
STAD	Negative regulation of viral genome replication →	+0.074	+0.111	<.001	<.001	3	18
STAD	Viral genome replication →	+0.069	+0.096	<.001	<.001	3	17
STAD	Regulation of cysteine-type endopeptidase activity →	+0.058	+0.105	<.001	<.001	3	17
STAD	Type I interferon production →	+0.068	+0.106	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,907 associations by consensus.

Positive regulation of canonical NF-kappaB signal transduction by AIPL1 expression — STAD

Explore this box plot interactively →