AIPL1

Across TCGA patient cohorts, AIPL1 mutation is significantly associated with the RNA expression of many other genes, with 1,374 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AIPL1-associated genes across cancer lineages are BOLA3P3, YTHDF3-AS1, and LINC01480. Each is linked with AIPL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both AIPL1-to-partner and partner-to-AIPL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BOLA3P3 grouped by AIPL1-low versus AIPL1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AIPL1→partner) and Y-score (partner→AIPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BOLA3P3 →	+0.296	+2.002	.002	.003	3	3
UCEC	YTHDF3-AS1 →	+0.785	+2.724	<.001	.003	3	2
SKCM	LINC01480 →	-0.716	-2.980	.007	.001	3	2
LUAD	RNA5SP73 →	+0.281	+3.285	.001	.009	3	2
LUAD	HMGN1P28 →	+0.250	+3.431	.002	.009	3	2
LUAD	DNAJB6P5 →	+0.050	+3.802	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,374 associations by consensus.

BOLA3P3 by AIPL1 expression — UCEC

Explore this box plot interactively →