AIPL1

Across TCGA cell cohorts, AIPL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 479 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible AIPL1-associated GO terms across cancer lineages are Regulation of mitochondrion organization, Golgi to plasma membrane protein transport, and Regulation of viral genome replication. Each is linked with AIPL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both AIPL1-to-partner and partner-to-AIPL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitochondrion organization grouped by AIPL1-low versus AIPL1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AIPL1→partner) and Y-score (partner→AIPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of mitochondrion organization →	+0.043	+0.013	.002	.007	3	3
OVARY	Golgi to plasma membrane protein transport →	+0.086	+0.047	<.001	.002	3	3
OVARY	Regulation of viral genome replication →	+0.080	+0.029	<.001	<.001	3	3
BREAST	Actin polymerization-dependent cell motility →	+0.089	+0.021	.003	.003	3	3
BREAST	Detection of abiotic stimulus →	-0.060	-0.024	.001	.007	3	3
LUNG_NSCLC_LUAD	Cellular response to thyroid hormone stimulus →	+0.116	+0.052	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 479 associations by consensus.

Regulation of mitochondrion organization by AIPL1 expression — SKIN

Explore this box plot interactively →