AIP

Across TCGA pan-cancer cohorts, AIP mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated AIP data layer compared with 25 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher AIP mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated AIP expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

COAD, PDAC, and LSCC are the cancer types where AIP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.919	1.000	.029	12	view →
PDAC	DFS	Quartile	All	0.869	0.705	.025	3	view →
LSCC	DFS	Quartile	II,III,IV	0.549	0.872	.033	2	view →
GBM	DFS	Quartile	All	0.695	0.878	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

AIP–COAD (DFS)

Open the COAD breakdown →