AIMP2

Across TCGA patient cohorts, AIMP2 protein abundance is significantly associated with the RNA expression of many other genes, with 21,529 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AIMP2-associated genes across cancer lineages are CNRIP1, PDE1B, and ZCCHC24. Each is linked with AIMP2 in more than 7 cancer types. Because this analysis shows association rather than direction, both AIMP2-to-partner and partner-to-AIMP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AIMP2 versus CNRIP1 in BRCA, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AIMP2→partner) and Y-score (partner→AIMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CNRIP1 →	-0.932	-0.217	<.001	<.001	3	8
OV	PDE1B →	-0.816	-0.229	<.001	<.001	3	8
BRCA	ZCCHC24 →	-1.258	-0.200	<.001	<.001	3	8
HNSC	GNG2 →	-0.852	-0.161	<.001	<.001	3	8
BRCA	TCF4 →	-0.824	-0.188	<.001	.001	3	8
BRCA	CHRDL1 →	-1.818	-0.236	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,529 associations by consensus.

AIMP2 vs CNRIP1 — BRCA

Explore this scatter interactively →