AIMP2

Across TCGA cell cohorts, AIMP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,276 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible AIMP2-associated GO terms across cancer lineages are Meiotic mismatch repair, Ribosome biogenesis, and Transcription by RNA polymerase I. Each is linked with AIMP2 in more than 14 cancer types. Because this analysis shows association rather than direction, both AIMP2-to-partner and partner-to-AIMP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Meiotic mismatch repair grouped by AIMP2-low versus AIMP2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AIMP2→partner) and Y-score (partner→AIMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Meiotic mismatch repair →	+0.152	+1.063	<.001	.009	3	15
OESOPHAGUS	Ribosome biogenesis →	+0.120	+0.969	<.001	.001	3	13
PANCREAS	Transcription by RNA polymerase I →	+0.087	+0.919	.002	<.001	2	14
KIDNEY	Mitotic spindle elongation →	+0.232	+0.802	.002	.003	3	13
KIDNEY	Mitotic spindle midzone assembly →	+0.232	+0.802	.002	.003	3	13
SKIN	Positive regulation of mitotic sister chromatid separation →	+0.125	+0.789	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,276 associations by consensus.

Meiotic mismatch repair by AIMP2 expression — OESOPHAGUS

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