Across TCGA pan-cancer cohorts, AIMP1P2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of AIMP1P2’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where AIMP1P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types AIMP1P2 is over-expressed in tumor.
KIRC and KIRP are the cancer types where AIMP1P2 tumor–normal differential expression is most reproducible.