AIM2

Across TCGA patient cohorts, AIM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,322 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AIM2-associated proteins across cancer lineages are ARHGAP45, AKNA_S316, and GRB2. Each is linked with AIM2 in more than 9 cancer types. Because this analysis shows association rather than direction, both AIM2-to-partner and partner-to-AIM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AIM2 versus ARHGAP45 in GBM, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AIM2→partner) and Y-score (partner→AIM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARHGAP45 →	+0.567	+1.036	<.001	<.001	3	10
LSCC	AKNA_S316 →	+0.620	+1.427	<.001	<.001	3	10
UCEC	GRB2 →	+0.387	+1.355	<.001	<.001	3	10
HNSC	WARS1 →	+0.924	+1.255	<.001	<.001	3	9
UCEC	WAS →	+0.635	+1.401	<.001	<.001	3	9
OV	RCSD1_S351 →	+0.741	+1.544	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,322 associations by consensus.

AIM2 vs ARHGAP45 — GBM

Explore this scatter interactively →