AIG1

Across TCGA pan-cancer cohorts, AIG1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated AIG1 data layer compared with 25 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher AIG1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated AIG1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

CCRCC, PDAC, and HNSC are the cancer types where AIG1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	II,III,IV	0.975	0.625	.002	55	view →
PDAC	DFS	Median	All	0.341	0.562	.003	26	view →
HNSC	OS	Median	IV	0.153	1.000	.045	6	view →
LSCC	OS	Median	II,III,IV	0.612	0.880	.015	4	view →
LUAD	DFS	Median	All	0.812	1.000	.015	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

AIG1–CCRCC (OS)

Open the CCRCC breakdown →