AIG1

Across TCGA patient cohorts, AIG1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,256 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible AIG1-associated proteins across cancer lineages are VTA1, AFDN, and EZR. Each is linked with AIG1 in more than 4 cancer types. Because this analysis shows association rather than direction, both AIG1-to-partner and partner-to-AIG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AIG1 versus VTA1 in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AIG1→partner) and Y-score (partner→AIG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	VTA1 →	+0.338	+0.346	<.001	.003	3	5
OV	AFDN →	+0.467	+0.541	<.001	<.001	3	4
OV	EZR →	+0.502	+0.391	<.001	.009	3	4
OV	MAP3K4 →	+0.233	+0.432	.004	.001	3	4
GBM	MAP7 →	+0.656	+0.386	<.001	.001	2	5
BRCA	MAP7_S365 →	+0.699	+0.737	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,256 associations by consensus.

AIG1 vs VTA1 — GBM

Explore this scatter interactively →