Across TCGA patient cohorts, AIFM3 RNA expression is significantly associated with the RNA expression of many other genes, with 14,754 significant associations in total. UVM shows the largest number of these associations.

The most reproducible AIFM3-associated genes across cancer lineages are LINC01637, HDAC10, and TRMT2A. Each is linked with AIFM3 in more than 31 cancer types. Because this analysis shows association rather than direction, both AIFM3-to-partner and partner-to-AIFM3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AIFM3→partner) and Y-score (partner→AIFM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	LINC01637 →	+1.983	+1.874	<.001	<.001	3	32
ACC	HDAC10 →	+1.036	+0.638	<.001	<.001	3	27
ACC	TRMT2A →	+1.105	+0.695	<.001	<.001	3	25
KIRC	LMNTD2 →	+1.103	+0.424	<.001	<.001	3	24
LAML	NOXA1 →	+1.315	+0.971	<.001	<.001	3	24
KIRP	GUSBP11 →	+0.630	+0.323	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,754 associations by consensus.

Exploration

AIFM3 survival (RNA) · tumor vs normal (RNA) · all AIFM3 data types