Across TCGA patient cohorts, AIFM3 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,630 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AIFM3-associated proteins across cancer lineages are MAP4K4, HPRT1, and HSP90B1. Each is linked with AIFM3 in more than 4 cancer types. Because this analysis shows association rather than direction, both AIFM3-to-partner and partner-to-AIFM3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AIFM3→partner) and Y-score (partner→AIFM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MAP4K4 →	-0.239	-0.221	<.001	.003	3	5
HNSC	HPRT1 →	+0.353	+0.501	<.001	.001	3	4
GBM	HSP90B1 →	-0.244	-0.799	<.001	<.001	3	4
LSCC	HTATIP2 →	+0.492	+0.612	<.001	<.001	3	4
GBM	IQSEC2 →	+0.300	+0.674	<.001	<.001	3	4
GBM	ZDHHC5 →	+0.245	+0.783	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,630 associations by consensus.

Exploration

AIFM3 survival (RNA) · tumor vs normal (RNA) · all AIFM3 data types