AIFM2

Across TCGA patient cohorts, AIFM2 RNA expression is significantly associated with the RNA expression of many other genes, with 18,306 significant associations in total. UVM shows the largest number of these associations.

The most reproducible AIFM2-associated genes across cancer lineages are TYSND1, ANXA7, and NQO1. Each is linked with AIFM2 in more than 28 cancer types. Because this analysis shows association rather than direction, both AIFM2-to-partner and partner-to-AIFM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AIFM2 versus TYSND1 in ACC, with a Pearson correlation of 0.62.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AIFM2→partner) and Y-score (partner→AIFM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	TYSND1 →	+0.872	+1.459	<.001	<.001	3	29
ACC	ANXA7 →	+0.877	+1.241	<.001	<.001	3	28
LUSC	NQO1 →	+2.249	+0.908	<.001	<.001	3	27
ACC	FAM241B →	+1.338	+1.355	<.001	<.001	3	27
DLBC	SQSTM1 →	+1.127	+0.661	<.001	.003	3	27
ESCA	PCBD1 →	+0.802	+0.778	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,306 associations by consensus.

AIFM2 vs TYSND1 — ACC

Explore this scatter interactively →