AIFM2

Across TCGA patient cohorts, AIFM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,174 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AIFM2-associated proteins across cancer lineages are IDE, ECT2_T359, and HTATIP2. Each is linked with AIFM2 in more than 6 cancer types. Because this analysis shows association rather than direction, both AIFM2-to-partner and partner-to-AIFM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AIFM2 versus IDE in CCRCC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AIFM2→partner) and Y-score (partner→AIFM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	IDE →	+0.251	+0.455	<.001	<.001	2	7
COAD	ECT2_T359 →	+0.848	+0.505	<.001	<.001	3	5
LUAD	HTATIP2 →	+0.468	+0.519	<.001	<.001	3	5
LSCC	RBBP5_S497 →	+0.613	+0.402	.001	.003	3	4
LUAD	SUPV3L1 →	+0.424	+0.437	<.001	.001	3	4
LUAD	IRS2_S736 →	+0.958	+0.539	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,174 associations by consensus.

AIFM2 vs IDE — CCRCC

Explore this scatter interactively →