AIFM2

Across TCGA cell cohorts, AIFM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,903 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible AIFM2-associated GO terms across cancer lineages are Vitamin K metabolic process, Regulation of cellular response to oxidative stress, and Fat cell proliferation. Each is linked with AIFM2 in more than 8 cancer types. Because this analysis shows association rather than direction, both AIFM2-to-partner and partner-to-AIFM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vitamin K metabolic process grouped by AIFM2-low versus AIFM2-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AIFM2→partner) and Y-score (partner→AIFM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Vitamin K metabolic process →	+0.139	+1.408	<.001	<.001	3	9
URINARY_TRACT	Regulation of cellular response to oxidative stress →	+0.177	+1.599	<.001	<.001	3	9
LUNG_SCLC	Fat cell proliferation →	+0.275	+1.250	.001	.002	3	8
BONE	Cellular response to nicotine →	+0.132	+1.166	.001	.004	3	8
SKIN	Extracellular vesicle biogenesis →	+0.084	+0.791	.001	.001	3	8
SOFT_TISSUE	Negative regulation of low-density lipoprotein particle receptor catabolic process →	+0.204	+1.700	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,903 associations by consensus.

Vitamin K metabolic process by AIFM2 expression — BLOOD_Myeloma

Explore this box plot interactively →