AIFM1

Across TCGA patient cohorts, AIFM1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,439 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AIFM1-associated proteins across cancer lineages are PHF6, CUL4B, and FMR1. Each is linked with AIFM1 in more than 6 cancer types. Because this analysis shows association rather than direction, both AIFM1-to-partner and partner-to-AIFM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AIFM1 versus PHF6 in GBM, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AIFM1→partner) and Y-score (partner→AIFM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PHF6 →	+0.437	+0.348	<.001	<.001	3	7
OV	CUL4B →	+0.364	+0.793	<.001	<.001	3	7
OV	FMR1 →	+0.524	+0.790	.001	.001	2	7
GBM	RNF113A →	+0.302	+0.287	.003	<.001	3	5
BRCA	SERPINA1 →	-0.646	-0.392	<.001	<.001	3	5
HNSC	HMGB3 →	+0.535	+0.435	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,439 associations by consensus.

AIFM1 vs PHF6 — GBM

Explore this scatter interactively →