AIF1L

Across TCGA patient cohorts, AIF1L mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AIF1L-associated genes across cancer lineages are Tuberin_pT1462 and Bim. Each is linked with AIF1L in more than 1 cancer types. Because this analysis shows association rather than direction, both AIF1L-to-partner and partner-to-AIF1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tuberin_pT1462 grouped by AIF1L-low versus AIF1L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AIF1L→partner) and Y-score (partner→AIF1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Tuberin_pT1462 →	+0.283	+3.009	.026	.019	3	1
UCEC	Bim →	-0.347	-3.169	.016	.020	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Tuberin_pT1462 by AIF1L expression — UCEC

Explore this box plot interactively →