Across TCGA patient cohorts, AIDA mutation is significantly associated with the RNA expression of many other genes, with 538 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AIDA-associated genes across cancer lineages are RN7SKP60, RN7SL598P, and SNRPGP8. Each is linked with AIDA in more than 2 cancer types. Because this analysis shows association rather than direction, both AIDA-to-partner and partner-to-AIDA results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AIDA→partner) and Y-score (partner→AIDA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP60 →	+0.212	+2.613	<.001	.007	3	3
COAD	RN7SL598P →	+0.466	+4.516	<.001	.009	3	2
UCEC	SNRPGP8 →	+0.127	+3.063	.001	.007	3	2
BRCA	BUD31P1 →	+0.068	+7.731	<.001	.009	3	1
UCEC	H2AC12 →	+0.789	+3.584	<.001	.002	3	1
UCEC	UHRF1 →	+1.201	+3.332	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 538 associations by consensus.

Exploration

AIDA survival (RNA) · tumor vs normal (RNA) · all AIDA data types