AICDA

Across TCGA cell cohorts, AICDA RNA expression is significantly associated with the go_rna of many other GO terms, with 1,617 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible AICDA-associated GO terms across cancer lineages are Minus-end-directed organelle transport along microtubule, Cell differentiation involved in kidney development, and Negative regulation of interferon-beta production. Each is linked with AICDA in more than 3 cancer types. Because this analysis shows association rather than direction, both AICDA-to-partner and partner-to-AICDA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Minus-end-directed organelle transport along microtubule grouped by AICDA-low versus AICDA-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AICDA→partner) and Y-score (partner→AICDA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Minus-end-directed organelle transport along microtubule →	+0.086	+1.595	<.001	.003	3	4
OVARY	Cell differentiation involved in kidney development →	+0.135	+0.153	<.001	.004	3	4
BLOOD_Lymphoma	Negative regulation of interferon-beta production →	+0.068	+1.788	<.001	<.001	3	4
UPPER_AERODIGESTIVE_TRACT	Integrated stress response signaling →	+0.073	+0.030	.004	.008	2	4
UPPER_AERODIGESTIVE_TRACT	L-amino acid catabolic process →	-0.056	-0.029	.005	.003	3	3
UPPER_AERODIGESTIVE_TRACT	Positive regulation of plasma cell differentiation →	+0.102	+0.048	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,617 associations by consensus.

Minus-end-directed organelle transport along microtubule by AICDA expression — BLOOD_Lymphoma

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