AHSA1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, AHSA1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated AHSA1 data layer compared with 27 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher AHSA1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated AHSA1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and COAD show a favorable association.

PDAC, LUAD, and COAD are the cancer types where AHSA1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PDACOSTertileII,III,IV0.6380.361.01414view →
LUADOSTertileAll0.6411.000.0087view →
COADDFSMedianIII,IV1.0000.897.0446view →
LSCCOSQuartileII,III,IV0.9270.615.0274view →
CCRCCOSMedianIV0.4511.000.0161view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

AHSA1–PDAC (OS)

Kaplan–Meier survival curve for AHSA1 mass-spec protein-high vs -low samples in PDAC.

Open the PDAC breakdown →

Exploration