AHSA1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, AHSA1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AHSA1-associated genes across cancer lineages are NTSR2, FAM205A, and NEXMIF. Each is linked with AHSA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AHSA1-to-partner and partner-to-AHSA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NTSR2 grouped by AHSA1-low versus AHSA1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AHSA1→partner) and Y-score (partner→AHSA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINENTSR2 →+0.082+3.793<.001.00731
LARGE_INTESTINEFAM205A →+0.025+4.614<.001.00231
LARGE_INTESTINENEXMIF →+0.319+4.196<.001.00231
BLOOD_LeukemiaOR4F15 →+0.006+5.201<.001.00631
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

NTSR2 by AHSA1 expression — LARGE_INTESTINE

Box plot of NTSR2 in AHSA1-low vs AHSA1-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration