AHDC1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, AHDC1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated AHDC1 data layer compared with 22 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher AHDC1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated AHDC1 expression acts as an unfavorable survival marker, although some lineages such as OV and CCRCC show a favorable association.

OV, CCRCC, and PDAC are the cancer types where AHDC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
OVDFSMedianAll1.0000.812.01012view →
CCRCCDFSQuartileII,III,IV0.7330.323.0106view →
PDACOSMedianII,III,IV0.3930.594.0196view →
LUADDFSMedianII,III,IV1.0000.798.0153view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

AHDC1–OV (DFS)

Kaplan–Meier survival curve for AHDC1 mass-spec protein-high vs -low samples in OV.

Open the OV breakdown →

Exploration