AHDC1

Across TCGA cell cohorts, AHDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,508 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AHDC1-associated GO terms across cancer lineages are Negative regulation of DNA-templated transcription initiation, Negative regulation of transcription initiation by RNA polymerase II, and Negative regulation of organelle assembly. Each is linked with AHDC1 in more than 16 cancer types. Because this analysis shows association rather than direction, both AHDC1-to-partner and partner-to-AHDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA-templated transcription initiation grouped by AHDC1-low versus AHDC1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AHDC1→partner) and Y-score (partner→AHDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of DNA-templated transcription initiation →	+0.140	+1.245	<.001	<.001	3	17
LARGE_INTESTINE	Negative regulation of transcription initiation by RNA polymerase II →	+0.140	+1.245	<.001	<.001	3	17
SOFT_TISSUE	Negative regulation of organelle assembly →	+0.087	+1.555	<.001	<.001	3	17
BREAST	Negative regulation of cilium assembly →	+0.076	+1.425	<.001	<.001	3	15
BLOOD_Lymphoma	Regulation of translational initiation →	+0.085	+1.511	<.001	<.001	3	15
STOMACH	Regulation of protein localization to nucleus →	+0.089	+1.671	.003	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,508 associations by consensus.

Negative regulation of DNA-templated transcription initiation by AHDC1 expression — LARGE_INTESTINE

Explore this box plot interactively →