AHDC1

Across TCGA cell cohorts, AHDC1 mutation is significantly associated with the RNA expression of many other genes, with 1,533 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AHDC1-associated genes across cancer lineages are PBOV1, UQCRFS1, and SLC25A51. Each is linked with AHDC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both AHDC1-to-partner and partner-to-AHDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PBOV1 grouped by AHDC1-low versus AHDC1-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AHDC1→partner) and Y-score (partner→AHDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	PBOV1 →	+0.055	+3.094	<.001	.001	3	3
CNS	UQCRFS1 →	+0.501	+3.067	.001	.009	3	3
LARGE_INTESTINE	SLC25A51 →	+0.593	+3.459	<.001	<.001	3	3
SOFT_TISSUE	PGLYRP4 →	+0.012	+4.369	<.001	.008	3	2
BREAST	SCYGR2 →	+0.116	+3.312	<.001	.004	3	2
CNS	UTP18 →	+0.431	+3.528	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,533 associations by consensus.

PBOV1 by AHDC1 expression — OVARY

Explore this box plot interactively →