AHCYP4

Across TCGA pan-cancer cohorts, AHCYP4 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of AHCYP4’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where AHCYP4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types AHCYP4 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

COAD, LUSC, and STAD are the cancer types where AHCYP4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AHCYP4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.142	<.001	7	view →
LUSC	Male	All	+0.032	<.001	4	view →
STAD	Female	All	+0.075	.038	2	view →
KIRC	Male	II,III,IV	−0.022	.036	1	view →
LUAD	All	All	+0.015	.017	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

AHCYP4–COAD

Open the COAD breakdown →